The advantage of intelligent devices is obvious: the device drivers on the host can be made in a much more generic fashion, there is no longer a need to change (and qualify!) drivers for every odd new device that is introduced.
For cabling and connectors there is a golden rule: use quality components. With bus speeds going up all the time a lot of grief can be saved by using good materials.
So, gold plated connectors, shielded cabling, sturdy connector hoods with strain reliefs etc are recommended.